S2P Process Design & Standards Senior Manager

Job Description General Summary: The Lead, Process Design & Standards is responsible for leading and advancing enterprise Source to Pay (S2P) process design and standards. This role serves as a senior process architect and steward for S2P, helping ensure clarity, consistency, scalability, and alignment with enterprise governance and strategy. Operating within the S2P Center of Excellence, this role focuses on how S2P should work across the organization and partners closely with Category and Sourcing teams, User Orchestration, and Execution Systems & Analytics COE teams to help ensure that process intent is translated into user experiences, systems, and insights—without owning execution, configuration, or operational reporting. Key Duties and Responsibilities: Set the Foundation: Process Architecture & Standards • Lead the design, documentation, and maintenance of end to end S2P, SRM and Category Strategy process frameworks, standards, policies, controls, and decision models. • Serve as a senior steward of S2P, SRM and Category Strtategy process integrity, helping drive consistency and scalability across categories, regions, and business units. • Define clear process decision guidance, handoffs, and control points across sourcing, contracting, buying channels, invoicing, and payment. • Advance process standards that align with enterprise governance, audit, and compliance expectations in partnership with Finance, Legal, Risk, and Compliance. Process Excellence & Optimization • Apply a market and benchmarking lens to assess S2P, SRM and Category Strategy process maturity and identify improvement opportunities. • Lead the design, documentation, and maintenance of end to end S2P, SRM, and Category Strategy process frameworks, standards, policies, controls, and decision models. • Serve as a senior steward of S2P, SRM, and Category Strategy process integrity, helping drive consistency and scalability across categories, regions, and business units. • Define and maintain process performance measures covering efficiency, effectiveness, compliance, and user experience. • Lead continuous improvement efforts, leveraging Lean and process excellence methodologies. • Use performance insights to inform prioritization of process enhancements and future state design decisions. Digital & Analytics Alignment • Advance process standards that are digitally enabled by design and aligned with current and future S2P, SRM and Category Strategy technology roadmaps. • Partner with the Execution Systems & Analytics COE to translate process standards into system design principles, configuration guardrails, and analytics requirements, without owning system configuration or reporting execution. • Provide clarity on process intent to support effective solution design, adoption sequencing, and insight generation. Cross COE & Enterprise Partnership • Partner with the User Orchestration COE to ensure process standards are reflected in intake design, buying channel guidance, and decision flows. • Partner with Category and Sourcing teams to embed enterprise process standards into category strategies and sourcing ways of working. • Support S2P governance forums with insight into process health, maturity, risks, and improvement priorities. Knowledge and Skills: 7+ years of experience in Procurement, S2P, or Supply Chain process design, optimization, or governance roles. Deep expertise in process standardization, controls, and performance management within complex organizations. Strong ability to influence outcomes in matrixed, cross functional environments. Strong verbal and written communication skills, with the ability to influence and build alignment across cross functional stakeholders. Experience developing and maintaining technical and process documentation, including standards, procedures, and decision frameworks. Education and Experience: Bachelor's degree #LI-Hybrid #LI-AA1 At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Pay Range: $139,100 - $208,700 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1-mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH-dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1. Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 16 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on LinkedIn, Facebook, Instagram, YouTube, and X We believe our culture is one of Vertex’s greatest strengths and a key enabler of our ability to deliver transformative medicines for patients who need them. Rooted in innovation, purpose and collaboration, our culture empowers people to take smart risks, challenge conventional thinking and do their best work. The diversity of our people is central to that culture. By bringing together individuals with different backgrounds, experiences and perspectives, we foster an environment where new ideas thrive, better decisions are made and breakthrough innovation is possible. We are committed to creating a workplace where everyone feels valued, included and connected to our shared mission, because we know that our unique culture and the collective strength of our people are what set Vertex apart.