Senior Manager, Global Treasury

Company Overview
Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.

Opportunity Overview
Rhythm Pharmaceuticals is seeking an experienced Senior Manager, Global Treasury to play a key role in the management, oversight, and continued development of the company’s global treasury function.

This position will have broad responsibility across global cash and liquidity management, treasury operations, controls and compliance, insurance, treasury technology, reporting and analytics, and financial risk management. The Senior Manager will combine technical expertise with hands-on operational leadership to deliver controlled, scalable, and efficient Treasury processes.

The role will serve as a cross-functional Treasury partner and a key Treasury lead working with banking partners, insurance brokers, and other external service providers. The role will also play a central role in the successful implementation, administration, and optimization of the Treasury Management System.

This role reports to the Director, Global Treasury and will work closely with them to independently lead substantial Treasury workstreams, develop recommendations, and manage day-to-day execution.

Responsibilities and Duties

• Global Cash and Liquidity Management
  •  Manage global cash and liquidity activities across multiple legal entities and currencies, including daily cash positioning and funding of operating entities.
  • Manage short- and medium-term cash flow forecasting, variance analysis, and identification of funding requirements or excess liquidity.
  • Develop recommendations for optimizing global liquidity cash concentration, intercompany funding, cash pooling, investment of excess cash, and funding strategies for review with the Director, Global Treasury.
  • Partner with Accounting, AP, Tax, Payroll, Supply Chain, and other stakeholders to improve forecasting accuracy and coordinate intercompany funding and cross-border cash movements in accordance with approved strategies.
  • Monitor contractual liquidity requirements, interest payments, financial covenants, and other corporate obligations; prepare analysis and recommendations for the Director and senior Finance leadership.

• Global Banking & Treasury Operations
  • Oversee the global bank account lifecycle, banking documentation, signatories, KYC requirements, and account rationalization in accordance with approved banking strategy and policies.
  • Manage day-to-day banking relationships, service levels, and bank fees; evaluate products and recommend significant relationship or structure changes to the Director
  • Ensure controlled execution of payments, cash transfers, funding activities, and other treasury transactions including effective administration of banking platforms.
  • Lead resolution of complex banking, payment, settlement, connectivity, and operational issues, escalating significant financial, control, or relationship matters as appropriate.
  • Recommend improvements to banking structures and Treasury processes to increase efficiency, scalability, and control.
  • Partner with Accounting on the administration and oversight of corporate credit card programs, including program performance, policy compliance, controls, and fraud prevention.

• Treasury Controls, Compliance & Audit
  • Manage and maintain Treasury's internal control framework and support compliance with company policies, SOX requirements, banking controls, and applicable regulatory requirements.
  • Serve as the primary day-to-day Treasury point of contact for internal and external audit and compliance reviews, coordinating significant findings and remediation plans with the Director.
  • Develop and maintain Treasury policies, procedures, controls, approval authorities, operating standards, and audit-ready supporting documentation, recommending updates for approval as appropriate.
  • Oversee access governance, , segregation of duties, authorized signers, and sensitive financial information across Treasury systems and banking platforms.
  • Identify control gaps or operational risks and execute remediation plans with the Director and relevant stakeholders.
  • Monitor compliance and reporting requirements related to investment, FX, banking, cash management, bank accounts, and financial arrangements.
• Insurance & Risk Management
  • Manage the day-to-day administration of the global corporate insurance program in partnership with Legal, Finance, HR, and external brokers.
  • Coordinate annual insurance renewals, underwriting data, coverage reviews, and internal stakeholder input; support senior stakeholders in evaluating significant coverage and program decisions.
  • Maintain organized audit-ready insurance policies, certificates, premiums, allocations, claim documentation, and related records.
  • Support claims administration, due diligence, and insurance requirements related to contracts, financing arrangements, international subsidiaries, clinical operations, and other business activities.
  • Manage letters of credit and other financial guarantees within approved terms and authority levels.
• Investments, Foreign Exchange (FX) & Financial Risk
  • Monitor short-term investment activities against policy, liquidity requirements, maturity, yield, and concentration risk, and prepare recommendations for review and approval.
  • Monitor global foreign currency exposures and support the development and execution of appropriate FX risk-management strategies.
  • Monitor interest-rate, counterparty, liquidity, and other treasury risks and provide analysis and recommendations to the Director.
• Treasury Systems, Technology & Process Improvement
  • Serve as a key Treasury lead and functional administrator for the Treasury Management System, including implementation, controls, integrations, enhancements, and ongoing optimization.
  • Lead Treasury automation and integration efforts across the TMS, ERP, banking platforms, investment providers, and other financial systems in partnership with IT, Accounting, and system owners.
  • Leverage technology data analytics, and automation to reduce manual processes and improve Treasury reporting and decision-making with appropriate review and judgment.
  • Maintain governance over Treasury master data, interfaces, and system controls; coordinate requirements, testing, documentation, and adoption of system enhancements.
• Treasury Reporting & Cross-Functional Partnership
  • Deliver timely Treasury reporting for the Director and senior Finance leadership, including cash, liquidity, investments, banking activity, FX exposures, working capital KPIs, and treasury risks.
  • Support budgeting, forecasting, financial reporting, audit, and strategic initiatives requiring Treasury expertise.
  • Serve as a Treasury subject matter expert and lead cross-functional work with Accounting, FP&A, Tax, Legal, AP, Payroll, IT, banks, brokers, and other partners

Qualifications and Skills

Required Skills

• 8+ years of progressive corporate treasury experience, with substantial work in global cash and liquidity management, banking operations, controls, and treasury operations.
• Bachelor's degree (BA or BS) in Finance, Accounting, Economics, Business Administration, or a related field.
• Demonstrated experience managing cash and liquidity across multiple entities and currencies including forecasting, banking structures, payments, intercompany funding, and investments.
• Direct experience with internal/external audit, SOX/internal controls, and treasury compliance, KYC, payment controls, bank portals, and user entitlements.
• Advanced Excel, financial modeling, and data analysis skills, with the ability to identify inconsistencies, errors, and trends in financial data.
• Demonstrated ability to develop controls, policies, procedures, and scalable operating processes and to administer a Treasury Management system.
• Experience leading cross-functional Treasury initiatives and coordinating internal stakeholders, financial institutions, technology providers, and external advisors.
• Strong written and verbal communication skills with the ability to develop well supported recommendations, influence stakeholders, and recognize when significant risks or decisions require escalation.
• Ability to remain disciplined under pressure, adapt priorities when urgent issues arise, and demonstrate sound judgment, accountability, and strong work ethics.
• Excellent analytical and problem-solving capabilities, including root cause analysis, early risks identification, and development of practical solutions.
• High degree of integrity, discretion, accuracy, attention to detail, organization and follow-through across competing priorities and deadlines.

Preferred Skills

• Experience in multinational, publicly traded companies and global banking environments.
• Certified Treasury Professional (CTP) designation.
• Experience in the life sciences, biotechnology, pharmaceutical, or healthcare industry.
• Experience with Treasury Management System implementation or optimization and ERP or banking-platform integrations.

This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs. This role may involve some travel.

The expected salary range for this position is $135,000 - $215,000. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This role may be eligible for benefits and other compensation such as restricted stock units.


More about Rhythm
We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.  Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism.

At Rhythm our core values are:

• We are committed to advancing scientific understanding to improve patients’ lives
• We are inspired to tackle tough challenges and have the courage to ask bold questions
• We are eager to learn and adapt
• We believe collaboration and ownership are foundational for our success
• We value the unique contribution each individual brings to furthering our mission

Inherent in our core values is the commitment to act ethically and with integrity in all we do.

Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law.

Headquartered in Boston, Rhythm is proud to have been named one of the Top Places to Work in Massachusetts.